Description

1-Piperazinamine, 4-(2-Chloro-10,11-Dihydrodibenzo(B,F)Thiepin-10-Yl)- n-((3,4-Dimethoxyphenyl)Methylene)- is a high-purity, complex organic intermediate of significant interest in advanced pharmaceutical synthesis. This compound matters because it serves as a critical building block for the development of novel therapeutic agents, particularly within the central nervous system (CNS) and psychopharmacological research domains. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries seeking to develop new drug candidates or optimize synthetic routes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel tricyclic and tetracyclic compounds with potential biological activity.
• CNS Drug Research: Used in the research and development of new psychotropic agents, including potential antidepressants and antipsychotics, due to its structural similarity to known pharmacophores.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses requiring a functionalized piperazine and dibenzothiepin moiety.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of complex molecules for clinical trials.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	1-Piperazinamine, 4-(2-Chloro-10,11-Dihydrodibenzo(B,F)Thiepin-10-Yl)- n-((3,4-Dimethoxyphenyl)Methylene)-
CAS No.	86758-93-2
Molecular Formula	C27H28ClN3O2S
Molecular Weight	494.05 g/mol
Synonyms	4-[(2-Chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)]-N-[(3,4-dimethoxyphenyl)methylidene]-1-piperazinamine; 4-(2-Chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)-N-[(3,4-dimethoxyphenyl)methylene]-1-piperazinamine; NSC 339579; 1-Piperazinamine, 4-(2-chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)-N-[(3,4-dimethoxyphenyl)methylene]-; (E)-4-(2-Chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)-N-((3,4-dimethoxybenzylidene))piperazin-1-amine
EINECS	Contact for details

Quality Control

Our 1-Piperazinamine, 4-(2-Chloro-10,11-Dihydrodibenzo(B,F)Thiepin-10-Yl)- n-((3,4-Dimethoxyphenyl)Methylene)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity consistent with cGMP guidelines for pharmaceutical intermediates. Certificates of Analysis (COA) detailing purity, impurities, and full characterization data are available upon request to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under an inert atmosphere if found to be easily oxidized. Keep away from strong acids and bases.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Maximum Impurity	≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.