Description

1-Piperazinamine, 4-(8-Chloro-10,11-Dihydrodibenzo(B,F)Thiepin-10-Yl)- n-(Phenylmethylene)- is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound is valued for its role as a key synthetic precursor in the development of active pharmaceutical ingredients (APIs), particularly within the central nervous system (CNS) therapeutic area. It is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of novel psychotropic and neuroactive drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Process Chemistry Development: Serves as a key starting material (KSM) or intermediate in scaling up API manufacturing processes.
• Reference Standard: Utilized as an analytical standard for quality control and method validation in pharmaceutical analysis.
• Biochemical Research: Investigated for its interaction with specific biological receptors and enzymes in preclinical studies.

Basic Information

Product Name	1-Piperazinamine, 4-(8-Chloro-10,11-Dihydrodibenzo(B,F)Thiepin-10-Yl)- n-(Phenylmethylene)-
CAS No.	86758-90-9
Molecular Formula	C25H24ClN3S
Molecular Weight	433.99 g/mol
Synonyms	4-[(8-Chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)]-N-(phenylmethylene)-1-piperazinamine; 4-[(8-Chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)]-N-benzylidene-1-piperazinamine; 86758-90-9; 4-(8-Chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)-N-(phenylmethylidene)piperazin-1-amine; (Z)-4-(8-chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)-N-(phenylmethylene)piperazin-1-amine; 4-(8-Chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)-N-(phenylmethylidene)-1-piperazinamine
EINECS	Contact for details

Quality Control

Our 1-Piperazinamine, 4-(8-Chloro-10,11-Dihydrodibenzo(B,F)Thiepin-10-Yl)- n-(Phenylmethylene)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.