Description

5-(4-Amino-3-Methoxybenzyl)-2,4-Thiazolidinedione is a high-purity, specialized organic compound belonging to the thiazolidinedione class, serving as a critical advanced intermediate in pharmaceutical research and development. Its molecular structure makes it a valuable scaffold for synthesizing novel therapeutic agents targeting metabolic and inflammatory pathways. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries seeking reliable, high-quality building blocks for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel thiazolidinedione-based drug candidates.
• Drug Discovery Research: Used as a core scaffold in medicinal chemistry for developing potential treatments for metabolic disorders.
• Biochemical Research: Employed in studies investigating PPAR (Peroxisome Proliferator-Activated Receptor) modulation and related biological pathways.
• Fine Chemical Synthesis: Serves as a precursor for the preparation of more complex, functionalized molecules in custom synthesis projects.
• Reference Standard: Can be utilized as an analytical standard for quality control and method development in API (Active Pharmaceutical Ingredient) manufacturing.

Basic Information

Product Name	5-(4-Amino-3-Methoxybenzyl)-2,4-Thiazolidinedione
CAS No.	86733-81-5
Molecular Formula	C11H12N2O3S
Molecular Weight	252.29 g/mol
Synonyms	5-[(4-Amino-3-methoxyphenyl)methyl]-2,4-thiazolidinedione; 5-(4-Amino-3-methoxybenzyl)thiazolidine-2,4-dione; AMTZD; 2,4-Thiazolidinedione, 5-[(4-amino-3-methoxyphenyl)methyl]-; 5-(4-Amino-3-methoxy-benzyl)-[1,3]thiazolidine-2,4-dione
EINECS	Contact for details

Quality Control

Our 5-(4-Amino-3-Methoxybenzyl)-2,4-Thiazolidinedione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.