Description

4-[4,4-Bis(4-Fluorophenyl)Butyl]-n-Ethyl-1-Piperazinecarboxamide Hydrochloride is a high-purity, synthetically derived organic compound primarily utilized as a critical pharmaceutical intermediate. Its value lies in its role as a key building block in the synthesis of advanced active pharmaceutical ingredients (APIs), particularly within the central nervous system (CNS) therapeutic area. This compound is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development and production of novel neuropharmacological agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug molecules targeting neurological pathways.
• Research & Development (R&D): Used in medicinal chemistry for the discovery and optimization of new chemical entities with potential therapeutic effects.
• Active Pharmaceutical Ingredient (API) Synthesis: Incorporated into the final chemical structure of APIs for drugs treating CNS disorders.
• Contract Manufacturing: Supplied to CDMOs for scale-up and commercial production under current Good Manufacturing Practice (cGMP) standards.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	4-[4,4-Bis(4-Fluorophenyl)Butyl]-n-Ethyl-1-Piperazinecarboxamide Hydrochloride
CAS No.	86725-37-3
Molecular Formula	C23H30F2N3O • HCl
Molecular Weight	441.96 g/mol (Free base: 405.50 g/mol)
Synonyms	1-Piperazinecarboxamide, 4-[4,4-bis(4-fluorophenyl)butyl]-N-ethyl-, monohydrochloride; N-Ethyl-4-[4,4-bis(4-fluorophenyl)butyl]piperazine-1-carboxamide hydrochloride; Fluspirilene Intermediate; Fluspirilene Related Compound; 86725-37-3; 4-(4,4-Bis(4-fluorophenyl)butyl)-N-ethylpiperazine-1-carboxamide hydrochloride
EINECS	Contact for details

Quality Control

Our 4-[4,4-Bis(4-Fluorophenyl)Butyl]-n-Ethyl-1-Piperazinecarboxamide Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation via IR and NMR, and stringent control of residual solvents and related substances. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring full traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.