Description

1-Piperazinepropanol, β-(((2,3-Dihydro-1,4-Benzodioxin-5-Yl)Oxy)Methyl)-4-(1-Oxo-3-(3,4,5-Trimethoxyphenyl)-2-Propenyl)-, Monohydrochloride is a high-purity, complex organic intermediate featuring a piperazine core functionalized with a benzodioxin and trimethoxyphenyl propenyl moiety. This compound matters for its role as a critical building block in advanced pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries working on central nervous system (CNS) and cardiovascular drug candidates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and cardiovascular pathways.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Serves as a building block for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Bioconjugation & Probe Development: Potential use in creating labeled compounds or probes for biological assays and diagnostic research.
• Library Synthesis: Valuable for generating diverse compound libraries in high-throughput screening for drug discovery.
• Academic Research: Employed in university and institutional labs for investigating new chemical entities and their biological activities.

Basic Information

Item	Detail
Product Name	1-Piperazinepropanol, β-(((2,3-Dihydro-1,4-Benzodioxin-5-Yl)Oxy)Methyl)-4-(1-Oxo-3-(3,4,5-Trimethoxyphenyl)-2-Propenyl)-, Monohydrochloride
CAS No.	86580-11-2
Molecular Formula	C27H34N2O7 • HCl
Molecular Weight	535.03 g/mol (free base: 498.57 g/mol)
Synonyms	4-[3-(3,4,5-Trimethoxyphenyl)-2-propenoyl]-1-[3-[(2,3-dihydro-1,4-benzodioxin-5-yl)oxy]-2-hydroxypropyl]piperazine Monohydrochloride; 1-[3-[(2,3-Dihydro-1,4-benzodioxin-5-yl)oxy]-2-hydroxypropyl]-4-[3-(3,4,5-trimethoxyphenyl)-2-propenoyl]piperazine Hydrochloride; 86580-11-2; Piperazine derivative 86580-11-2; (E)-1-(3-((2,3-Dihydrobenzo[b][1,4]dioxin-5-yl)oxy)-2-hydroxypropyl)-4-(3-(3,4,5-trimethoxyphenyl)acryloyl)piperazine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-Piperazinepropanol derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) documenting purity (typically by HPLC), identity (by IR, NMR), and impurity profiles are provided with every shipment. We support compliance with relevant guidelines and can tailor specifications to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider desiccated environments.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0% (Total impurities ≤ 3.0%)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.