Description

n-[(S)-5,6,7,9-Tetrahydro-9-Oxo-1,2,3,10-Tetramethoxybenzo[A]Heptalen-7-Yl]Propionamide is a high-purity, complex organic compound with a defined stereocenter, serving as a critical advanced intermediate in pharmaceutical research and development. Its precise molecular architecture makes it invaluable for the synthesis of novel therapeutic agents, particularly in oncology and neurology. This compound is essential for B2B clients in the fine chemical, pharmaceutical R&D, and contract manufacturing sectors who require reliable, high-quality building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of potential anticancer and neuroactive drug candidates.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Serves as a critical intermediate in scaling up synthetic routes for Active Pharmaceutical Ingredients (APIs).
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for exploring new synthetic methodologies and biological targets.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control.

Basic Information

Item	Detail
Product Name	n-[(S)-5,6,7,9-Tetrahydro-9-Oxo-1,2,3,10-Tetramethoxybenzo[A]Heptalen-7-Yl]Propionamide
CAS No.	86495-10-5
Molecular Formula	C23H27NO6
Molecular Weight	413.47 g/mol
Synonyms	(S)-7-Propionamido-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalene; NSC 339586; Benzo[a]heptalen-7-propionamide, 5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxo-, (7S)-; Colchiceine amide derivative; Tetrahydrocolchicine derivative
EINECS	Contact for details

Quality Control

Our n-[(S)-5,6,7,9-Tetrahydro-9-Oxo-1,2,3,10-Tetramethoxybenzo[A]Heptalen-7-Yl]Propionamide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic identification (NMR, IR, MS). A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.