Description

3-(4-Chloro-Phenyl)-Piperazin-2-One is a high-purity organic compound belonging to the piperazinone class, serving as a critical building block in advanced chemical synthesis. Its value lies in providing a versatile and functionalized scaffold for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. This intermediate is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries focused on innovation and process development.

Application

• Pharmaceutical Intermediate: Key synthetic precursor for the research and development of new therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the creation of novel pesticides and herbicides, leveraging its chlorophenyl and piperazinone motifs for biological activity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and performance materials.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects and scale-up activities.

Basic Information

Product Name	3-(4-Chloro-Phenyl)-Piperazin-2-One
CAS No.	86147-28-6
Molecular Formula	C10H11ClN2O
Molecular Weight	210.66 g/mol
Synonyms	3-(4-Chlorophenyl)piperazin-2-one; 1-(4-Chlorophenyl)-2-oxopiperazine; 4-Chlorophenylpiperazinone; 2-Piperazinone, 3-(4-chlorophenyl)-; 86147-28-6; 3-(p-Chlorophenyl)-2-piperazinone; 3-(4-Chlorophenyl)-2-piperazinone; 3-(4-Chloro-phenyl)-piperazin-2-one
EINECS	Contact for details

Quality Control

Our 3-(4-Chloro-Phenyl)-Piperazin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment aligns with cGMP principles where applicable, supporting our customers' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.