Description

Lipoxin C4 is a specialized, high-purity eicosanoid signaling molecule derived from docosahexaenoic acid (DHA), playing a crucial role in the resolution phase of inflammation. This compound is valued for its potent anti-inflammatory and pro-resolving bioactivity, making it a critical research tool and a candidate for therapeutic development. It is primarily sought by researchers and developers in the pharmaceutical, biotechnology, and advanced life science sectors for applications in immunology, inflammation research, and the development of novel resolution pharmacology.

Application

• Biomedical Research: Used as a reference standard and active agent in studies of inflammation resolution, immune modulation, and cellular signaling pathways.
• Pharmaceutical R&D: Serves as a lead compound or molecular template for the development of new anti-inflammatory and pro-resolving therapeutic agents.
• Cell Culture & In Vitro Studies: Applied in cell-based assays to investigate its effects on macrophage function, neutrophil apoptosis, and cytokine production.
• Biochemical Analysis: Employed as a calibrant in analytical methods such as LC-MS/MS and ELISA for the quantification of specialized pro-resolving mediators (SPMs) in biological samples.
• Mechanistic Studies: Utilized to explore receptor-ligand interactions, particularly with the ALX/FPR2 receptor, to understand downstream signaling events.

Basic Information

Product Name	Lipoxin C4
CAS No.	85951-62-8
Molecular Formula	C26H38O5
Molecular Weight	430.58 g/mol
Synonyms	LXC4; (4Z,7Z,10Z,12E,14E,16Z,19Z)-4,7,10,12,14,16,19-Docosaheptaenoic acid, 5,6-epoxy-17,18-dihydroxy-; 5(S),6(S)-Epoxy-17(R),18(S)-dihydroxy-4Z,7Z,10Z,12E,14E,16Z,19Z-docosaheptaenoic acid; 17(R),18(S)-DiHETE; 17,18-Dihydroxyeicosatetraenoic acid derivative; DHA-derived Lipoxin; Specialized Pro-resolving Mediator (SPM).
EINECS	Contact for details

Quality Control

Our Lipoxin C4 is produced and handled under strict quality protocols to ensure batch-to-batch consistency and high chemical integrity. Each lot is characterized using advanced analytical techniques, including NMR and high-resolution mass spectrometry, to confirm structure and purity. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and stability is provided with every shipment to support your critical research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. Store away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Solubility	Soluble in ethanol, DMSO; slightly soluble in aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.