Description

19-Nor-10-Ketovitamin D2 is a chemically modified, biologically active vitamin D analog. This compound is significant for its role as a key synthetic intermediate in the research and development of novel therapeutic agents targeting vitamin D receptor pathways. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing treatments for conditions related to calcium metabolism, bone health, and cellular differentiation.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of advanced vitamin D analogs and prodrugs for clinical research.
• Biochemical Research: Used as a reference standard and active compound in studies investigating vitamin D receptor (VDR) activation and metabolism.
• Drug Discovery: Serves as a precursor in medicinal chemistry programs aimed at creating new therapeutics for osteoporosis, psoriasis, and secondary hyperparathyroidism.
• Academic Research: Employed in university and institutional labs to study the structure-activity relationships (SAR) of secosteroids.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for producing high-value, low-volume specialty chemicals.

Basic Information

Product Name	19-Nor-10-Ketovitamin D2
CAS No.	85925-89-9
Molecular Formula	C₂₇H₄₂O₂
Molecular Weight	398.63 g/mol
Synonyms	19-Nor-10-Oxovitamin D2; (5Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3β-ol-24-one; 10-Keto-19-norvitamin D2; 19-Nor-10-ketoergocalciferol; 24-Oxo-19-norvitamin D2; 19-Nor-10-oxoergocalciferol
EINECS	Contact for details

Quality Control

Our 19-Nor-10-Ketovitamin D2 is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) to prevent oxidation and degradation. Keep the container in a cool, dry, and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.