Description

1H-Imidazol-2-Amine, 4,5-Dihydro-n-(4-(3-(4-(2-Methoxyphenyl)-1-Piperazinyl)Propoxy)Phenyl)-, Pentahydrochloride is a high-purity, complex organic salt primarily utilized as a key pharmaceutical intermediate. This compound is critical for researchers and manufacturers developing novel therapeutic agents, particularly within the central nervous system (CNS) and cardiovascular domains. Its primary value lies in enabling the synthesis of advanced drug candidates, making it essential for pharmaceutical R&D, contract manufacturing organizations (CMOs), and fine chemical suppliers serving the global life sciences industry.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting neurological and cardiovascular pathways.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Preclinical Studies: Serves as a starting material or reference standard in pharmacological and toxicological testing during drug discovery phases.
• Contract Synthesis: Supplied to CMOs and CDMOs for custom synthesis projects and scale-up manufacturing under cGMP conditions.
• Reference Standard: Used as a high-purity analytical standard for method development and quality control in API manufacturing.

Basic Information

Product Name	1H-Imidazol-2-Amine, 4,5-Dihydro-n-(4-(3-(4-(2-Methoxyphenyl)-1-Piperazinyl)Propoxy)Phenyl)-, Pentahydrochloride
CAS No.	85883-94-9
Molecular Formula	C23H32Cl5N5O2
Molecular Weight	579.80 g/mol
Synonyms	1H-Imidazol-2-amine, 4,5-dihydro-N-[4-[3-[4-(2-methoxyphenyl)-1-piperazinyl]propoxy]phenyl]-, pentahydrochloride; 4,5-Dihydro-2-imidazolamine, N-[4-[3-[4-(2-methoxyphenyl)-1-piperazinyl]propoxy]phenyl]-, pentahydrochloride; UNII-5Q2N5WQ0QJ; 5Q2N5WQ0QJ; 2-Imidazolin-2-amine derivative pentahydrochloride; (4,5-Dihydro-1H-imidazol-2-yl)-[4-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propoxy]phenyl]amine pentahydrochloride
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for pharmaceutical development. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical parameters such as assay, related substances, and residual solvents. We support development from research to commercial scale with consistent quality aligned with ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.