Description

4-n-Benzyl-2-Hydroxymethylpiperazine is a versatile piperazine derivative that serves as a crucial building block in advanced organic synthesis. This compound is valued for its bifunctional structure, featuring both a benzyl-protected amine and a hydroxymethyl group, which enables its use in constructing complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the piperazine core contributes to biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the production of specialty polymers with tailored properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme inhibition.
• Custom Synthesis and Contract Manufacturing: An essential starting material for custom chemical synthesis services catering to the fine chemical and life science industries.

Basic Information

Product Name	4-n-Benzyl-2-Hydroxymethylpiperazine
CAS No.	85817-34-1
Molecular Formula	C12H18N2O
Molecular Weight	206.28 g/mol
Synonyms	2-(Hydroxymethyl)-1-benzylpiperazine; 1-Benzyl-2-(hydroxymethyl)piperazine; 4-Benzyl-2-hydroxymethylpiperazine; 2-Piperazinemethanol, 1-benzyl-; N-Benzyl-2-(hydroxymethyl)piperazine; 85817-34-1; 1-Benzylpiperazine-2-methanol
EINECS	Contact for details

Quality Control

Our 4-n-Benzyl-2-Hydroxymethylpiperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis. We provide a Certificate of Analysis (COA) with every shipment, detailing all specifications and test results to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.