Description

[1R,6R,(+)]-1α-[[(1S,4As,8As)-Decahydro-5,5,8A-Trimethyl-2-Methylenenaphthalene-1β-Yl]Methyl]-5β-Hydroxy-4-(Hydroxymethyl)-7-Oxabicyclo[4.1.0]Hepta-3-Ene-2-One is a high-purity, complex sesquiterpene lactone derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral intermediate and building block for the development of novel bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the synthesis of terpenoid-based therapeutics, natural product analogs, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the research and development of novel drug candidates, particularly in anti-inflammatory and anticancer therapeutic areas.
• Natural Product Synthesis: Building block for the total or semi-synthesis of complex terpenoids and sesquiterpene lactones found in medicinal plants.
• Asymmetric Catalysis Research: Valuable substrate for studying and developing new stereoselective synthetic methodologies.
• Chemical Biology Probes: Used in the design and synthesis of molecular probes to study biological pathways and protein interactions.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Advanced Material Synthesis: Potential monomer or precursor for synthesizing specialty polymers with unique optical or structural properties.

Basic Information

Product Name	[1R,6R,(+)]-1α-[[(1S,4As,8As)-Decahydro-5,5,8A-Trimethyl-2-Methylenenaphthalene-1β-Yl]Methyl]-5β-Hydroxy-4-(Hydroxymethyl)-7-Oxabicyclo[4.1.0]Hepta-3-Ene-2-One
CAS No.	85754-70-7
Molecular Formula	C22H34O4
Molecular Weight	362.51 g/mol
Synonyms	(+)-1α-[[(1S,4aS,8aS)-Decahydro-5,5,8a-trimethyl-2-methylenenaphthalen-1β-yl]methyl]-5β-hydroxy-4-(hydroxymethyl)-7-oxabicyclo[4.1.0]hept-3-ene-2-one; 1α-[[(1S,4aS,8aS)-Decahydro-5,5,8a-trimethyl-2-methylenenaphthalen-1β-yl]methyl]-5β-hydroxy-4-(hydroxymethyl)-7-oxabicyclo[4.1.0]hept-3-ene-2-one; Sesquiterpene lactone derivative; 7-Oxabicyclo[4.1.0]hepta-3-ene-2-one derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our [1R,6R,(+)]-1α-[[(1S,4As,8As)-Decahydro-5,5,8A-Trimethyl-2-Methylenenaphthalene-1β-Yl]Methyl]-5β-Hydroxy-4-(Hydroxymethyl)-7-Oxabicyclo[4.1.0]Hepta-3-Ene-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and MS to ensure identity, purity, and chiral integrity. Certificates of Analysis (COA) with detailed chromatographic data are provided and available upon request to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). For long-term storage, consider storage under inert atmosphere at -20°C to maximize stability. The container should be kept in a well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.