Description

1-0-Octadecyl 2-0-Acetyl Sn-Glycero-3-Phosphorylcholine is a synthetic, high-purity phospholipid derivative, specifically an acetylated alkylphosphocholine. This compound is a critical building block in advanced lipid research and formulation, valued for its role in creating stable, functional lipid assemblies. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for developing liposomal drug delivery systems, biomimetic membranes, and other specialized lipid-based applications.

Application

• Liposomal Drug Delivery: A key component in the formulation of long-circulating and targeted liposomes for encapsulating therapeutic agents.
• Biomimetic Membrane Research: Used to create model membrane systems for studying cell membrane properties, protein-lipid interactions, and membrane dynamics.
• Diagnostic Reagents: Incorporated into lipid-based reagents for diagnostic assays and imaging applications.
• Biomaterials & Coatings: Serves as a surface-modifying agent to create biocompatible coatings for medical devices and implants.
• Cosmetic Formulations: Employed in high-end cosmetic products for its skin-barrier repair and moisturizing properties in lipid-based nanoemulsions.
• Biophysical Studies: Essential for calorimetry, spectroscopy, and microscopy studies investigating lipid bilayer structure and phase behavior.

Basic Information

Product Name	1-0-Octadecyl 2-0-Acetyl Sn-Glycero-3-Phosphorylcholine
CAS No.	85733-91-1
Molecular Formula	C28H58NO7P
Molecular Weight	551.73 g/mol
Synonyms	1-O-Octadecyl-2-O-acetyl-sn-glycero-3-phosphocholine; OAGPC; 1-Stearyl-2-acetyl-sn-glycero-3-phosphocholine; C18:0 LysoPAF; Alkylacetylphosphatidylcholine; 1-Octadecyl-2-acetyl-sn-glycerol-3-phosphorylcholine; 1-O-Octadecyl-2-acetyl-glycero-3-phosphocholine; Acetylated Alkyl LysoPC
EINECS	Contact for details

Quality Control

Our 1-0-Octadecyl 2-0-Acetyl Sn-Glycero-3-Phosphorylcholine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and LC-MS for identity and impurity profiling. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP-grade requirements. Specifications are designed to meet the exacting standards of pharmaceutical development and advanced material science.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. The material is hygroscopic and moisture-sensitive; allow the sealed vial to equilibrate to room temperature before opening to minimize condensation. For long-term stability, store desiccated.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Assay (NMR / HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.