Description

4-Cyclopentyl-α-((Methyl(Phenylmethyl)Amino)Methyl)Benzenemethanol Hydrogen Maleate is a high-purity, non-racemic chiral compound primarily utilized as a critical intermediate in advanced pharmaceutical synthesis. Its value lies in its specific stereochemistry and functional groups, which make it a key building block for developing active pharmaceutical ingredients (APIs) with targeted therapeutic effects. This product is essential for research institutions and manufacturers in the pharmaceutical industry focused on creating novel drug candidates, particularly in areas requiring complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the multi-step synthesis of proprietary drug molecules and active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new therapeutic agents.
• Process Chemistry: Employed in route scouting and scale-up optimization for the commercial production of complex organic compounds.
• Asymmetric Synthesis: Acts as a building block in reactions requiring high enantiomeric purity for the construction of stereogenic centers.

Basic Information

Product Name	4-Cyclopentyl-α-((Methyl(Phenylmethyl)Amino)Methyl)Benzenemethanol Hydrogen Maleate
CAS No.	85689-97-0
Molecular Formula	C25H31NO5
Molecular Weight	425.52 g/mol
Synonyms	Benzenemethanol, 4-cyclopentyl-α-[[methyl(phenylmethyl)amino]methyl]-, (αR)-, (2Z)-2-butenedioate (1:1); (R)-4-Cyclopentyl-α-((methyl(benzyl)amino)methyl)benzenemethanol maleate salt; 4-Cyclopentyl-α-((N-methylbenzylamino)methyl)benzyl alcohol hydrogen maleate; Frovatriptan Maleate Intermediate; Frovatriptan Related Compound; (R)-Frovatriptan Impurity; Benzyl alcohol derivative intermediate; Contact for EINECS details.

Quality Control

Our 4-Cyclopentyl-α-((Methyl(Phenylmethyl)Amino)Methyl)Benzenemethanol Hydrogen Maleate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets stringent specifications for pharmaceutical R&D use. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.