Description

Leucyl-Alanyl-Dansylethylenediamine is a specialized dansyl-labeled dipeptide derivative designed for advanced biochemical research and analytical applications. This compound is valued for its role as a high-sensitivity fluorescent probe and substrate in enzymatic studies, particularly for protease and peptidase activity assays. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors for developing assays, studying enzyme kinetics, and creating novel detection methodologies.

Application

• Fluorescent Protease Substrate: Acts as a sensitive, fluorogenic substrate for the study of protease and peptidase enzyme activity and inhibition.
• Biochemical Research Reagent: Used in academic and industrial R&D for investigating protein digestion, peptide sequencing, and enzyme mechanism studies.
• Diagnostic Assay Development: Employed in the design and validation of high-throughput screening (HTS) assays and clinical diagnostic kits for enzymatic markers.
• Cell Biology Studies: Utilized as a tracer or probe in cellular imaging and localization studies due to its dansyl fluorophore.
• Pharmaceutical QC Testing: Applied in quality control laboratories for testing the activity and specificity of enzyme-based biopharmaceuticals.
• Peptide Synthesis & Labeling Reference: Serves as a reference standard or intermediate in the synthesis of custom fluorescently-labeled peptides.

Basic Information

Product Name	Leucyl-Alanyl-Dansylethylenediamine
CAS No.	85589-23-7
Molecular Formula	C28H44N6O5S
Molecular Weight	576.76 g/mol
Synonyms	L-Leucyl-L-alanyl-N5-(5-dimethylaminonaphthalene-1-sulfonyl)-N1-ethyl-1,2-diaminoethane; Leu-Ala-Dansyl-Ethylenediamine; Dansyl-Ethylenediamine-Leu-Ala; Dns-EDA-Leu-Ala; N5-(Dansyl)-N1-ethyl-1,2-diaminoethane-Leucyl-Alanine; Fluorescent Leucyl-Alanyl Derivative; Protease Fluorogenic Substrate; 5-Dimethylaminonaphthalene-1-sulfonyl ethylenediamine leucyl alanine amide
EINECS	Contact for details

Quality Control

Our Leucyl-Alanyl-Dansylethylenediamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and spectrophotometry for fluorophore integrity, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatograms and spectral data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. Due to its hygroscopic nature, the container should be kept in a desiccated environment. Allow the product to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to light brown powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Fluorescence Properties	Conforms to typical emission/excitation profile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.