Description

4A-[[4-(2-Ethoxy-2-Phenyl-Ethyl)Piperazin-1-Yl]Methyl]-8-Methoxy-2,3,4,9B-Tetrahydro-1H-Dibenzofuran-4-Ol Dihydrochloride is a high-purity, complex organic salt with significant pharmacological research interest. This compound matters as a key synthetic intermediate or reference standard in the development of novel therapeutic agents targeting the central nervous system. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and advanced chemical manufacturers engaged in the synthesis of new chemical entities (NCEs).

Application

• Pharmaceutical Research & Development (R&D): Serves as a critical building block or reference standard in the synthesis and optimization of new drug candidates.
• Preclinical Studies: Used as a high-purity material for pharmacological screening, mechanism of action studies, and early-stage toxicology assessments.
• Process Chemistry Development: Employed as an intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Analytical Method Development: Acts as a certified reference material (CRM) for validating HPLC, LC-MS, and other analytical methods in quality control laboratories.
• Academic Research: Utilized in university and institutional labs for medicinal chemistry projects and biochemical pathway investigations.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Item	Details
Product Name	4A-[[4-(2-Ethoxy-2-Phenyl-Ethyl)Piperazin-1-Yl]Methyl]-8-Methoxy-2,3,4,9B-Tetrahydro-1H-Dibenzofuran-4-Ol Dihydrochloride
CAS No.	85418-66-2
Molecular Formula	C29H39N2O4Cl2 (or C29H39N2O4 · 2HCl)
Molecular Weight	Approx. 551.54 g/mol (Contact for exact details)
Synonyms	8-Methoxy-4a-({4-[2-ethoxy-2-phenylethyl]piperazin-1-yl}methyl)-2,3,4,4a,9b-hexahydro-1H-dibenzo[b,d]furan-4-ol dihydrochloride; 4a-({4-[2-Ethoxy-2-phenylethyl]piperazin-1-yl}methyl)-8-methoxy-2,3,4,4a,9b-hexahydro-1H-dibenzo[b,d]furan-4-ol dihydrochloride; 85418-66-2; CAS 85418-66-2; 1H-Dibenzofuran-4-ol, 4a-[[4-(2-ethoxy-2-phenylethyl)-1-piperazinyl]methyl]-8-methoxy-2,3,4,4a,9b-hexahydro-, dihydrochloride
EINECS	Contact for details

Quality Control

Our 4A-[[4-(2-Ethoxy-2-Phenyl-Ethyl)Piperazin-1-Yl]Methyl]-8-Methoxy-2,3,4,9B-Tetrahydro-1H-Dibenzofuran-4-Ol Dihydrochloride is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research applications. All products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.