Description

5-(Aminosulphonyl)-n-[(2-Ethyloctahydro-1H-Isoindol-1-Yl)Methyl]-2-Methoxybenzamide Monohydrochloride is a high-purity, specialized organic compound primarily utilized as a key pharmaceutical intermediate or active pharmaceutical ingredient (API) building block. Its complex molecular structure, featuring an isoindoline core linked to a substituted benzamide, makes it a valuable scaffold in medicinal chemistry for developing novel therapeutics. This compound is essential for research and development laboratories and GMP manufacturing facilities focused on central nervous system (CNS) agents, receptor modulators, or other targeted drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of proprietary drug candidates, particularly those targeting neurological pathways.
• Active Pharmaceutical Ingredient (API) Development: Used as a core structural component in the research and scale-up of new chemical entities (NCEs).
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of lead compounds.
• Biochemical Tool Compound: May be utilized in vitro and in vivo studies to investigate specific biological mechanisms and receptor interactions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Reference Standard: Provided as a high-purity standard for analytical method development, validation, and quality control testing.

Basic Information

Product Name	5-(Aminosulphonyl)-n-[(2-Ethyloctahydro-1H-Isoindol-1-Yl)Methyl]-2-Methoxybenzamide Monohydrochloride
CAS No.	85409-39-8
Molecular Formula	C19H30N3O4S • HCl
Molecular Weight	436.0 g/mol (approx.)
Synonyms	2-Methoxy-5-sulfamoyl-N-[(2-ethyloctahydro-1H-isoindol-1-yl)methyl]benzamide hydrochloride; 5-Sulfamoyl-2-methoxy-N-[(2-ethyloctahydroisoindol-1-yl)methyl]benzamide monohydrochloride; 85409-39-8; Benzamide, 5-(aminosulfonyl)-2-methoxy-N-[[(2-ethyloctahydro-1H-isoindol-1-yl)]methyl]-, monohydrochloride; UNII-8W9M5N401Z; 8W9M5N401Z
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality systems. Every batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We employ advanced analytical techniques including HPLC, NMR, and MS to ensure the material meets exacting specifications for pharmaceutical R&D and pre-clinical use. Specifications can be aligned with ICH guidelines for impurities, and custom purity grades are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.