Description

2-Chloro-3-(Piperazinyl)Pyrazine is a heterocyclic organic compound featuring a pyrazine core substituted with chlorine and a piperazine moiety. This specific molecular architecture makes it a valuable and versatile pharmaceutical intermediate and research chemical for medicinal chemistry programs. It is primarily sought after by R&D and production teams in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs). The compound's structure is pivotal in constructing molecules with potential biological activity, particularly in central nervous system (CNS) and oncology research.

Application

• Key Intermediate in Pharmaceutical Synthesis: Serves as a critical building block for the development of new drug candidates, especially those targeting neurological disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to explore new therapeutic avenues.
• Precursor for Biologically Active Molecules: Employed in the synthesis of complex heterocycles with potential kinase inhibitory or receptor modulating activity.
• Chemical Reference Standard: Utilized in analytical laboratories for method development, validation, and quality control of related substances.
• Academic and Institutional Research: A valuable reagent for universities and research institutes studying heterocyclic chemistry and drug discovery methodologies.

Basic Information

Product Name	2-Chloro-3-(Piperazinyl)Pyrazine
CAS No.	85386-99-8
Molecular Formula	C8H11ClN4
Molecular Weight	198.65 g/mol
Synonyms	2-Chloro-3-piperazin-1-ylpyrazine; 3-Chloro-6-(1-piperazinyl)pyrazine; 1-(3-Chloro-2-pyrazinyl)piperazine; 2-Chloro-3-(1-piperazinyl)pyrazine; 85386-99-8; 2-Chloro-3-piperazinopyrazine; Piperazine, 1-(3-chloro-2-pyrazinyl)-
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-(Piperazinyl)Pyrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.