Description

Dihydroacarbose is a potent α-glucosidase inhibitor, a key intermediate in the synthesis of the anti-diabetic drug acarbose. Its primary value lies in enabling the production of pharmaceuticals that help manage postprandial blood glucose levels in patients with type 2 diabetes. This high-purity intermediate is essential for manufacturers in the pharmaceutical and fine chemical sectors focused on metabolic disorder therapeutics.

Application

• Pharmaceutical Intermediate: Critical synthesis precursor for the production of Acarbose, a first-line medication for type 2 diabetes.
• Biochemical Research: Used as a reference standard and tool compound in enzymatic studies targeting α-glucosidase and α-amylase inhibition.
• Active Pharmaceutical Ingredient (API) Development: Serves as a building block in the R&D of novel carbohydrate-based therapeutic agents.
• Process Chemistry: Employed in scale-up and optimization of manufacturing processes for complex oligosaccharide drugs.
• Quality Control: Utilized as an analytical standard for the purity testing and validation of acarbose and related drug substances.

Basic Information

Product Name	Dihydroacarbose
CAS No.	85382-75-8
Molecular Formula	C25H43NO18
Molecular Weight	645.61 g/mol
Synonyms	BAY g 5421 (Dihydro derivative); O-4,6-Dideoxy-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-α-D-glucopyranosyl-(1→4)-O-α-D-glucopyranosyl-(1→4)-D-glucopyranose; Dihydro-Acarbose; Acarbose Impurity D; 4,6-Dideoxy-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-α-D-glucopyranosyl-(1→4)-α-D-glucopyranosyl-(1→4)-D-glucopyranose
EINECS	Contact for details

Quality Control

Our Dihydroacarbose is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing purity, residual solvents, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.