Description

2,4-Dihydro-4-[4-[4-(4-Methoxyphenyl)Piperazin-1-Yl]Phenyl]-3H-1,2,4-Triazol-3-One, Sodium Salt is a high-purity, synthetically derived chemical compound with significant utility in advanced research and development. This compound matters as a key intermediate or active pharmaceutical ingredient (API) in the synthesis of novel therapeutic agents, particularly those targeting the central nervous system. It is primarily needed by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and fine chemical suppliers serving the global life sciences sector.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of potential antipsychotic or neuroactive drug candidates.
• Biochemical Research: Used as a reference standard or tool compound in pharmacological studies, particularly for receptor binding assays.
• Contract Synthesis: Supplied to CMOs for the custom manufacturing of proprietary drug substances under GMP conditions.
• Academic Research: Utilized in university and institutional labs for medicinal chemistry programs and structure-activity relationship (SAR) studies.
• Preclinical Development: Serves as a starting material for the preparation of compounds used in animal model studies.
• Analytical Standard: Employed as a high-purity calibrant in HPLC, LC-MS, and other analytical methods for quality control.

Basic Information

Product Name	2,4-Dihydro-4-[4-[4-(4-Methoxyphenyl)Piperazin-1-Yl]Phenyl]-3H-1,2,4-Triazol-3-One, Sodium Salt
CAS No.	85098-66-4
Molecular Formula	C19H20N5O2•Na
Molecular Weight	373.39 g/mol
Synonyms	4-[4-[4-(4-Methoxyphenyl)-1-piperazinyl]phenyl]-2,4-dihydro-3H-1,2,4-triazol-3-one, sodium salt; 1,2,4-Triazol-3-one, 2,4-dihydro-4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-, sodium salt; Sodium 4-(4-(4-(4-methoxyphenyl)piperazin-1-yl)phenyl)-4H-1,2,4-triazol-3-olate; Nefazodone Impurity Sodium Salt; Nefazodone Related Compound A Sodium Salt
EINECS	Contact for details

Quality Control

Our 2,4-Dihydro-4-[4-[4-(4-Methoxyphenyl)Piperazin-1-Yl]Phenyl]-3H-1,2,4-Triazol-3-One, Sodium Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing comprehensive test results, including assay and impurity profiles by HPLC, are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.