Description

α-(1-Hydroxycyclohexyl)-Biphenylacetic Acid, (+)- is a high-purity, single-enantiomer organic compound of significant interest in advanced pharmaceutical synthesis. This compound matters as a critical chiral intermediate or building block for developing novel active pharmaceutical ingredients (APIs) with enhanced efficacy and reduced side-effect profiles. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the production of stereospecific drugs and other bioactive molecules.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs) and other therapeutic agents.
• Agrochemical Research: Used in the development of enantiomerically pure pesticides and herbicides for improved target specificity.
• Fine Chemical Synthesis: Serves as a versatile precursor in asymmetric synthesis and catalysis for producing complex organic molecules.
• Academic & Industrial R&D: Valuable reference standard and starting material for medicinal chemistry programs and process optimization studies.
• Biochemical Research: Potential use in studying enzyme-substrate interactions and chiral recognition processes.

Basic Information

Product Name	α-(1-Hydroxycyclohexyl)-Biphenylacetic Acid, (+)-
CAS No.	85045-68-7
Molecular Formula	C20H22O3
Molecular Weight	310.39 g/mol
Synonyms	(+)-α-(1-Hydroxycyclohexyl)-Biphenylacetic Acid; (S)-2-(4-Biphenylyl)-2-hydroxycyclohexaneacetic Acid; Dexketoprofen Impurity; Dexketoprofen Related Compound; Dexketoprofen Acid Impurity; (S)-2-(Biphenyl-4-yl)-2-hydroxycyclohexylacetic Acid; Dexketoprofen Precursor
EINECS	Contact for details

Quality Control

Our α-(1-Hydroxycyclohexyl)-Biphenylacetic Acid, (+)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider using a desiccant in the container.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (S)-enantiomer
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.