Description

Diflunisal Phosphate is a phosphate ester prodrug of the non-steroidal anti-inflammatory drug (NSAID) diflunisal. This chemical modification is designed to enhance the solubility and bioavailability of the parent compound, making it a valuable intermediate in advanced pharmaceutical development. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the formulation of novel analgesic and anti-inflammatory medications.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of prodrug formulations aimed at improving drug delivery and efficacy.
• Analgesic Research: Used in R&D for developing new long-acting pain management therapies.
• Anti-inflammatory Drug Development: Serves as a building block for creating enhanced NSAID variants with optimized pharmacokinetic profiles.
• Prodrug Synthesis: Employed in studies focusing on phosphate ester chemistry to mask active drug molecules for controlled release.
• Reference Standard: Acts as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical labs.

Basic Information

Product Name	Diflunisal Phosphate
CAS No.	84958-45-2
Molecular Formula	C14H11F2O6P
Molecular Weight	344.21 g/mol
Synonyms	2',4'-Difluoro-4-hydroxybiphenyl-3-yl dihydrogen phosphate; Diflunisal Dihydrogen Phosphate; 5-(2,4-Difluorophenyl)-2-hydroxyphenyl Dihydrogen Phosphate; Diflunisal Phosphate Ester; [1,1'-Biphenyl]-3-ol, 2',4'-difluoro-4-hydroxy-, 3-(dihydrogen phosphate)
EINECS	Contact for details

Quality Control

Our Diflunisal Phosphate is manufactured under strict quality systems to ensure high purity and consistency suitable for pharmaceutical research and development. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and specifications can be aligned with pharmacopeial standards (e.g., USP, EP) upon request to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and stored in a dark environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.