Description

2-Piperazinonicotinonitrile is a high-value, nitrogen-rich heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its unique piperazine-nicotinonitrile scaffold makes it a versatile intermediate for constructing complex molecular architectures with targeted biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Chemical Biology Probe: Serves as a scaffold for designing molecular probes to study enzyme function and protein-protein interactions.
• Material Science: Investigated as a monomer or additive for creating specialized polymers with unique electronic or binding properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and discovery chemistry projects.

Basic Information

Product Name	2-Piperazinonicotinonitrile
CAS No.	84951-44-0
Molecular Formula	C10H11N5
Molecular Weight	201.23 g/mol
Synonyms	2-(Piperazin-1-yl)nicotinonitrile; Nicotinonitrile, 2-(1-piperazinyl)-; 2-Piperazin-1-ylpyridine-3-carbonitrile; 3-Cyano-2-piperazin-1-ylpyridine; 84951-44-0; 2-Piperazinyl-3-cyanopyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Piperazinonicotinonitrile is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the identity, purity, and consistency required for sensitive R&D and scale-up processes. A detailed Certificate of Analysis (COA) including HPLC purity, NMR, and mass spectrometry confirmation is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.