Description

5-Pyrimidinecarboxamide, 2-Amino-n-(8-(p-Fluorobenzyl)-3-β-Nortropa Nyl)-4-Methoxy-, Monomaleate is a high-purity, specialized pharmaceutical intermediate and research chemical. This compound is critical for the development and synthesis of novel therapeutic agents, particularly in the field of central nervous system (CNS) research. It is primarily utilized by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and academic research institutions engaged in advanced medicinal chemistry. The monomaleate salt form ensures enhanced stability and handling characteristics for precise formulation work.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates targeting neurological pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in API manufacturing.
• Biochemical Research: Investigated for its interaction with specific biological receptors and enzymes in preclinical studies.
• Contract Synthesis: Supplied to CMOs for the cGMP or non-GMP production of bespoke compounds for clinical trials.

Basic Information

Product Name	5-Pyrimidinecarboxamide, 2-Amino-n-(8-(p-Fluorobenzyl)-3-β-Nortropa Nyl)-4-Methoxy-, Monomaleate
CAS No.	84923-18-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	2-Amino-N-[8-[(4-fluorophenyl)methyl]-3β-nortropanyl]-4-methoxy-5-pyrimidinecarboxamide monomaleate; 84923-18-2; Nortropa Nyl Pyrimidinecarboxamide Monomaleate; p-Fluorobenzyl Nortropa Nyl Pyrimidine Derivative; 2-Amino-4-methoxy-N-(8-(4-fluorobenzyl)-3β-nortropan-3α-yl)pyrimidine-5-carboxamide maleate (1:1)
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all critical quality attributes. We support development and commercial projects with quality standards suitable for research use, non-GMP, or cGMP applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.