Description

Ganglioside, Gd1b-Lactone CAS NO 84861-74-5 is a specific, complex glycosphingolipid derivative, a lactonized form of the GD1b ganglioside. This compound is of significant interest in advanced biochemical and neurological research due to its unique structural conformation and role in cellular membrane dynamics. It is primarily utilized by research institutions and pharmaceutical developers focused on neurobiology, immunology, and the study of carbohydrate-protein interactions.

Application

• Neurological Research: As a key tool for studying ganglioside function in neural cell membranes, synaptic transmission, and neurodegenerative disease models.
• Immunological Studies: Investigation of its role as an antigen or modulator in autoimmune disorders and immune cell signaling pathways.
• Biochemical Standard: Use as a high-purity reference standard for analytical methods such as HPLC, MS, and NMR in quality control laboratories.
• Pharmaceutical R&D: Exploration in drug discovery programs targeting ganglioside-mediated processes, including potential therapeutic agents.
• Glycobiology Research: Fundamental research on carbohydrate structure, lactone formation stability, and glycolipid metabolism.
• Diagnostic Development: Potential use in the development of assays and reagents for detecting specific antibodies or biomarkers.

Basic Information

Product Name	Ganglioside, Gd1b-Lactone
CAS No.	84861-74-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	GD1b Lactone; Ganglioside GD1b Lactone; Lactonized GD1b; GD1b Monolactone; II3(NeuAc)2-LcOse4Cer Lactone; Disialosylgalactosylgloboside Lactone; Neu5Acα2-8Neu5Acα2-3Galβ1-3GalNAcβ1-4Galβ1-4Glcβ1-1'Cer Lactone
EINECS	Contact for details

Quality Control

Our Ganglioside, Gd1b-Lactone is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for biochemical reagents, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 95%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Specific Rotation	Contact for details
Solubility	Soluble in chloroform/methanol mixtures

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.