Description

(5R)-3-[[(Aminocarbonyl)Oxy]Methyl]-6β-[(R)-1-Hydroxyethyl]-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Hept-2-Ene-2-Carboxylic Acid Sodium Salt is a high-purity pharmaceutical intermediate and a key derivative in the synthesis of advanced β-lactam antibiotics. This compound is critical for research and development in medicinal chemistry, particularly for creating novel antibacterial agents with enhanced efficacy. It is primarily utilized by pharmaceutical manufacturers, R&D laboratories, and fine chemical suppliers focused on active pharmaceutical ingredient (API) production.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of next-generation carbapenem and penem class antibiotics.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the research and scale-up production of novel antibacterial drugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new therapeutic agents against resistant bacterial strains.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses requiring a high-purity, complex β-lactam core structure.
• Reference Standard: Acts as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical analysis.

Basic Information

Item	Details
Product Name	(5R)-3-[[(Aminocarbonyl)Oxy]Methyl]-6β-[(R)-1-Hydroxyethyl]-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Hept-2-Ene-2-Carboxylic Acid Sodium Salt
CAS No.	84845-58-9
Molecular Formula	C12H15N2O7SNa
Molecular Weight	354.31 g/mol
Synonyms	Sodium (5R,6R)-6-[(1R)-1-Hydroxyethyl]-3-[(carbamoyloxy)methyl]-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate; Carbapenem Derivative Sodium Salt; 4-Thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid Derivative; Antibiotic Intermediate 84845-58-9; Sodium 6-(1-Hydroxyethyl)-3-(carbamoyloxymethyl)-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate; (5R,6R)-6-[(1R)-1-Hydroxyethyl]-3-{[(aminocarbonyl)oxy]methyl}-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid Sodium Salt
EINECS	Contact for details

Quality Control

Our (5R)-3-[[(Aminocarbonyl)Oxy]Methyl]-6β-[(R)-1-Hydroxyethyl]-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Hept-2-Ene-2-Carboxylic Acid Sodium Salt is manufactured under strict quality systems. Products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and identity confirmation suitable for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each batch to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccants or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.