Description

Arglabin CAS NO 84692-91-1 is a naturally occurring sesquiterpene lactone compound of significant pharmaceutical interest. This molecule matters for its potent and selective biological activity, particularly as an inhibitor of farnesyl transferase, which has driven extensive research into its therapeutic potential. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of high-purity reference standards for applications in oncology and immunology studies.

Application

• Pharmaceutical Research & Development: Key intermediate or active pharmaceutical ingredient (API) in the development of novel anticancer therapies.
• Reference Standard: High-purity material for use as a certified reference standard (CRS) in analytical method development, validation, and quality control.
• Biochemical Studies: Tool compound for investigating the farnesyl transferase inhibition pathway and its role in cell proliferation and signal transduction.
• Preclinical Studies: Used in in vitro and in vivo models to evaluate efficacy, pharmacokinetics, and toxicology profiles.
• Natural Product Isolation & Synthesis: Serves as a target molecule for total synthesis projects or as a marker compound in the analysis of plant extracts.

Basic Information

Product Name	Arglabin
CAS No.	84692-91-1
Molecular Formula	C15H20O3
Molecular Weight	248.32 g/mol
Synonyms	(-)-Arglabin; Arglabin D; NSC 714977; (3aR,4S,5S,9aR,9bS)-5-Ethenyl-3a,4,5,9a-tetrahydro-4-hydroxy-3,6,9-trimethylazuleno[4,5-b]furan-2,7-dione; 1(10),4(11)-Guaiadien-12,8-olide
EINECS	Contact for details

Quality Control

Our Arglabin is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR, MS), purity assay by HPLC, and control of related substances. A Certificate of Analysis (COA) detailing all test results and specifications is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.