Description

4-Hydroxy-1-Phenethylpiperidine-4-Carbonitrile Monohydrochloride is a high-purity pharmaceutical intermediate and fine chemical building block. This compound is valued for its specific piperidine-based structure, which is crucial for synthesizing more complex active pharmaceutical ingredients (APIs) and other specialty chemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for process development and scale-up.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel therapeutic agents, particularly those targeting the central nervous system.
• Chemical Synthesis: Used as a versatile precursor for constructing complex nitrogen-containing heterocycles in medicinal chemistry.
• Research & Development (R&D): Serves as a critical reagent in academic and industrial R&D labs for exploring new chemical entities and reaction pathways.
• Agrochemical Development: Potential intermediate in the research and synthesis of new crop protection agents and pesticides.
• Material Science: Can be utilized in the development of specialty polymers and advanced functional materials requiring specific amine functionalities.

Basic Information

Product Name	4-Hydroxy-1-Phenethylpiperidine-4-Carbonitrile Monohydrochloride
CAS No.	84682-26-8
Molecular Formula	C14H18N2O•HCl
Molecular Weight	266.77 g/mol
Synonyms	1-(2-Phenylethyl)-4-piperidinecarbonitrile, 4-hydroxy-, monohydrochloride; 4-Hydroxy-1-(2-phenylethyl)-4-piperidinecarbonitrile hydrochloride; 4-Cyano-4-hydroxy-1-phenethylpiperidine hydrochloride; 1-Phenethyl-4-cyano-4-hydroxypiperidine hydrochloride; 4-Hydroxy-1-phenethyl-4-piperidinecarbonitrile HCl; 84682-26-8; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-1-Phenethylpiperidine-4-Carbonitrile Monohydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.