Description

Ethyl cis-4-[(4-Chloro-2-Nitrophenyl)Amino]-3-Hydroxypiperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate of significant synthetic importance. This compound matters for its role as a critical building block in the development of complex active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and other therapeutic areas. Pharmaceutical R&D teams and fine chemical manufacturers need this material for its precise stereochemistry and functional groups, which enable efficient synthesis pathways.

Application

This specialized intermediate is designed for high-value synthesis applications, primarily within the pharmaceutical and advanced research sectors.

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for neurological and psychiatric disorders.
• Active Pharmaceutical Ingredient (API) Development: Used in research and process development for constructing complex molecular architectures in new APIs.
• Chemical Biology & Medicinal Chemistry Research: Serves as a valuable scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Process Chemistry & Scale-Up: Employed in optimizing synthetic routes from laboratory to pilot and commercial scale production.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	Ethyl cis-4-[(4-Chloro-2-Nitrophenyl)Amino]-3-Hydroxypiperidine-1-Carboxylate
CAS No.	84682-25-7
Molecular Formula	C14H18ClN3O5
Molecular Weight	343.76 g/mol
Synonyms	Ethyl (3R,4S)-4-[(4-Chloro-2-nitrophenyl)amino]-3-hydroxypiperidine-1-carboxylate; cis-4-[(4-Chloro-2-nitrophenyl)amino]-3-hydroxypiperidine-1-carboxylic acid ethyl ester; 1-Carbethoxy-4-[(4-chloro-2-nitrophenyl)amino]-3-hydroxypiperidine; 84682-25-7; UNII-7I2G8VQ8JN
EINECS	Contact for details

Quality Control

Our Ethyl cis-4-[(4-Chloro-2-Nitrophenyl)Amino]-3-Hydroxypiperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. Our production adheres to cGMP principles where applicable, ensuring reliability for critical pharmaceutical development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.