Description

1,2-Benzisoxazol-3-Ylacetyl Chloride is a high-purity, reactive chemical intermediate of significant importance in advanced organic synthesis. Its value lies in its role as a key acylating agent for introducing the 1,2-benzisoxazole moiety, a privileged scaffold in medicinal chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical industry, particularly those developing new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of novel drug candidates, especially those targeting the central nervous system.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its bioactive heterocyclic structure.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for constructing complex heterocyclic compounds and exploring new reaction pathways.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the scalable production of APIs that contain the benzisoxazole functional group.
• Material Science Precursor: Investigated for the synthesis of specialized polymers and organic electronic materials with unique properties.

Basic Information

Product Name	1,2-Benzisoxazol-3-Ylacetyl Chloride
CAS No.	84637-43-4
Molecular Formula	C9H6ClNO2
Molecular Weight	195.60 g/mol
Synonyms	3-(Chloroacetyl)-1,2-benzisoxazole; 1,2-Benzisoxazole-3-acetyl chloride; (1,2-Benzisoxazol-3-yl)acetyl chloride; 2-(1,2-Benzisoxazol-3-yl)acetyl chloride; 3-Acetyl-1,2-benzisoxazole chloride
EINECS	Contact for details

Quality Control

Our 1,2-Benzisoxazol-3-Ylacetyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.