Description

Eicosapentaenoic Acid Ethyl Ester (EPA-EE) is a highly purified ethyl ester derivative of the essential ω-3 fatty acid, Eicosapentaenoic Acid. This compound is valued for its enhanced stability and bioavailability compared to its free acid form, making it a critical intermediate for high-value nutraceutical and pharmaceutical formulations. It is primarily sought by manufacturers in the dietary supplement, functional food, and advanced pharmaceutical sectors for its well-documented cardiovascular and anti-inflammatory benefits.

Application

• Pharmaceutical Intermediates: A key starting material for the synthesis of prescription-grade ω-3 medications and high-concentration therapeutic formulations.
• Dietary Supplement Encapsulation: The preferred form for softgel and capsule production due to its superior oxidative stability and purity profile.
• Functional Food & Beverage Fortification: Used to enrich products like dairy alternatives, infant formula, and medical nutrition with standardized EPA content.
• Clinical Research & Reference Standards: Serves as a high-purity standard in analytical laboratories for method development and quality control testing.
• Biochemical Research: Utilized in cell culture studies and metabolic research to investigate lipid pathways and inflammatory responses.
• Cosmeceutical Ingredients: Incorporated into topical formulations for its skin-conditioning and anti-aging properties.

Basic Information

Product Name	Eicosapentaenoic Acid Ethyl Ester
CAS No.	84494-70-2
Molecular Formula	C22H34O2
Molecular Weight	330.51 g/mol
Synonyms	EPA Ethyl Ester; EPA-EE; Ethyl Eicosapentaenoate; Ethyl (5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-Eicosapentaenoate; Ethyl (all-Z)-5,8,11,14,17-Eicosapentaenoate; Timnodonic Acid Ethyl Ester; ω-3 Ethyl Ester (EPA); 20:5 n-3 Ethyl Ester
EINECS	Contact for details

Quality Control

Our Eicosapentaenoic Acid Ethyl Ester is produced under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including GC and HPLC analysis, to ensure it meets stringent purity and identity specifications. Certificates of Analysis (COA) detailing assay, related substances, and heavy metal content are provided with every shipment. We support compliance with cGMP, FDA, and REACH requirements for global market access.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen) at 2-8°C to minimize oxidation and maintain stability. Keep away from heat and ignition sources. For long-term storage, freezing at -20°C or below is recommended.

Specification

Item	Specification
Appearance	Clear, pale yellow to colorless oily liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 90.0% (EPA-EE)
Total ω-3 Ethyl Esters	≥ 95.0%
Peroxide Value	≤ 5.0 meq/kg
Anisidine Value	≤ 20.0
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.