Description

1-n-Cbz-3-Methyl Piperazine is a versatile and high-purity piperazine derivative, primarily used as a critical building block in pharmaceutical synthesis. This compound is essential for medicinal chemists developing new active pharmaceutical ingredients (APIs), particularly in the areas of central nervous system (CNS) drugs and oncology. Its protected amine functionality makes it a valuable intermediate for researchers and manufacturers in the fine chemical and pharmaceutical industries requiring precise molecular architecture.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, especially in CNS and anticancer research.
• Peptide Mimetics & PROTACs: Used in the construction of complex molecules like peptide mimetics and Proteolysis Targeting Chimeras (PROTACs).
• Agrochemical Synthesis: Serves as a precursor in the development of advanced crop protection agents and pesticides.
• Ligand & Catalyst Development: Employed in the creation of specialized ligands and organocatalysts for asymmetric synthesis.
• Chemical Biology Research: Utilized as a molecular scaffold or linker in probe development and biochemical studies.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	1-n-Cbz-3-Methyl Piperazine
CAS No.	84477-85-0
Molecular Formula	C13H18N2O2
Molecular Weight	234.30 g/mol
Synonyms	1-Carbobenzoxy-3-methylpiperazine; 3-Methyl-1-(phenylmethoxycarbonyl)piperazine; 1-(Benzyloxycarbonyl)-3-methylpiperazine; N-Cbz-3-Methylpiperazine; 1-[(Benzyloxy)carbonyl]-3-methylpiperazine; 3-Methyl-1-Cbz-piperazine; 1-(Benzyloxycarbonyl)-3-methylpiperazine; Benzyl 3-methylpiperazine-1-carboxylate
EINECS	Contact for details

Quality Control

Our 1-n-Cbz-3-Methyl Piperazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with the standards expected by the pharmaceutical industry for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.