Description

Deoxymannojirimycin is a potent and specific inhibitor of α-mannosidase I, a key enzyme in N-linked oligosaccharide processing. This compound is a critical research tool for studying glycoprotein biosynthesis, protein folding, and quality control within the endoplasmic reticulum. It is essential for scientists and manufacturers in the pharmaceutical, biotechnology, and life science research sectors investigating glycosylation pathways, viral infectivity, and the development of therapeutic agents.

Application

• Glycobiology Research: A fundamental tool for inhibiting N-linked glycan processing to study the structure and function of glycoproteins.
• Antiviral Research: Investigated for its potential to disrupt the glycosylation of viral envelope proteins, which can impair viral assembly and infectivity.
• Cell Biology Studies: Used to induce the accumulation of misfolded glycoproteins in the endoplasmic reticulum (ER), facilitating research on ER-associated degradation (ERAD) and unfolded protein response (UPR).
• Biopharmaceutical Development: Employed in the development and quality control of therapeutic proteins, such as monoclonal antibodies, to understand and control glycosylation patterns critical for efficacy and safety.
• Enzymology: Serves as a specific enzymatic inhibitor for mechanistic studies of glycosidase enzymes and for high-throughput screening assays.

Basic Information

Product Name	Deoxymannojirimycin
CAS No.	84444-90-6
Molecular Formula	C6H13NO4
Molecular Weight	163.17 g/mol
Synonyms	1-Deoxymannojirimycin; D-Mannitol, 1,5-dideoxy-1,5-imino-; (2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-triol; Mannostatin A; Deoxymannojirimycin hydrochloride (salt form); DMJ; dMNJ
EINECS	Contact for details

Quality Control

Our Deoxymannojirimycin is produced under strict quality management protocols. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and specific tests for residual solvents and moisture. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.