Description

Benzamide, n-[(1-Ethyl-2-Pyrrolidinyl)Methyl]-2-Hydroxy-6-Methoxy-, (S)- is a high-purity, chiral benzamide derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical pharmaceutical intermediate or reference standard in the synthesis and analysis of complex active pharmaceutical ingredients (APIs). It is primarily required by pharmaceutical companies, contract research organizations (CROs), and academic research institutions focused on neuroscience and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel therapeutic agents, particularly those targeting neurological pathways.
• Reference Standard: Used for analytical method development, validation, and quality control (QC) in pharmaceutical manufacturing to ensure product identity and purity.
• Research Chemical: Employed in preclinical and pharmacological studies to investigate structure-activity relationships (SAR) and receptor binding affinity.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor or core structure in the development of new drug candidates, especially in the CNS domain.
• Process Chemistry: Utilized in route scouting and optimization for scalable and efficient API synthesis.
• Metabolite Synthesis: Used to synthesize potential drug metabolites for toxicological and pharmacokinetic studies.

Basic Information

Product Name	Benzamide, n-[(1-Ethyl-2-Pyrrolidinyl)Methyl]-2-Hydroxy-6-Methoxy-, (S)-
CAS No.	84226-04-0
Molecular Formula	C16H24N2O3
Molecular Weight	292.38 g/mol
Synonyms	(S)-N-[(1-Ethyl-2-pyrrolidinyl)methyl]-2-hydroxy-6-methoxybenzamide; (S)-2-Hydroxy-6-methoxy-N-[(1-ethyl-2-pyrrolidinyl)methyl]benzamide; (S)-EMHB; (S)-Enantiomer of Remoxipride Metabolite; L-765,314 (potential research code); (S)-(-)-N-[(1-Ethyl-2-pyrrolidinyl)methyl]salicylamide 6-methyl ether; A chiral benzamide derivative
EINECS	Contact for details

Quality Control

Our Benzamide, n-[(1-Ethyl-2-Pyrrolidinyl)Methyl]-2-Hydroxy-6-Methoxy-, (S)- is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for chiral purity and assay, residual solvent analysis, and identity confirmation (IR, MS). We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or cGMP guidelines. Specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (S-enantiomer)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.