Description

Dl-Dihexylphosphatidylcholine * (Hexyl Ether) CAS NO 84223-27-8 is a synthetic phospholipid derivative, specifically a dihexyl ether analog of phosphatidylcholine. This compound is valued for its unique amphiphilic properties and enhanced stability profile compared to natural phospholipids. It serves as a critical functional excipient and structural component in advanced pharmaceutical formulations and life science research, particularly for creating stable, tunable lipid-based delivery systems.

Application

• Lipid Nanoparticle (LNP) Formulation: A key structural lipid for constructing stable nanoparticles for mRNA, siRNA, and other nucleic acid delivery.
• Liposome and Niosome Development: Used to engineer vesicles with modified membrane fluidity and permeability for targeted drug delivery.
• Biomimetic Membrane Studies: Serves as a synthetic analog in model membrane systems to study biophysical properties and protein-lipid interactions.
• Pharmaceutical Excipient: Functions as a solubilizer, emulsifier, and penetration enhancer in topical and injectable formulations.
• Diagnostic Reagent Component: Incorporated into reagents and assays that require stable, defined phospholipid matrices.
• Cosmetic Formulations: Used in high-end skincare products for its emulsifying and skin-barrier reinforcing properties.

Basic Information

Product Name	Dl-Dihexylphosphatidylcholine * (Hexyl Ether)
CAS No.	84223-27-8
Molecular Formula	C28H60NO7P
Molecular Weight	553.76 g/mol
Synonyms	1,2-Di-O-hexyl-sn-glycero-3-phosphocholine; Dihexyl PC ether; 1,2-Dihexyl-rac-glycero-3-phosphocholine; Phosphatidylcholine, 1,2-dihexyl ether; DLPC Hexyl Ether; Synthetic C6 Phosphatidylcholine Ether; Hexyl Ether Phospholipid; L-α-Phosphatidylcholine, 1,2-dihexyl ether
EINECS	Contact for details

Quality Control

Our Dl-Dihexylphosphatidylcholine (Hexyl Ether) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, MS), to ensure it meets the stringent requirements for pharmaceutical and research applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. The material is hygroscopic and light-sensitive; allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white waxy solid or viscous liquid
Identification (HPLC, NMR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solvent Residues (GC)	Meets ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.