Description

Wilforlide A Acetate is a bioactive diterpenoid compound derived from the *Tripterygium wilfordii* plant. This high-purity reference standard is critical for pharmaceutical research and development, particularly in the study of anti-inflammatory and immunosuppressive mechanisms. It serves as an essential analytical standard for quality control in the production of herbal extracts and modern therapeutics. Researchers and manufacturers in the pharmaceutical, biotechnology, and nutraceutical industries rely on it for its consistent biological activity and structural integrity.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification, assay, and purity testing of herbal extracts and finished products.
• Bioactivity Research: A key compound for in-vitro and in-vivo studies investigating anti-inflammatory, immunosuppressive, and anti-tumor activities.
• Natural Product Isolation & Analysis: Serves as a critical marker compound for the standardization and quality assessment of *Tripterygium wilfordii* (Thunder God Vine) extracts.
• Drug Discovery & Development: Utilized as a lead compound or intermediate in the synthesis and development of novel small-molecule therapeutics.
• Academic & Contract Research: Essential for pharmacological studies in university and CRO (Contract Research Organization) laboratories.
• Quality Control Laboratories: Employed in HPLC, LC-MS, and NMR methods development and validation for herbal medicine quality assurance.

Basic Information

Product Name	Wilforlide A Acetate
CAS No.	84104-80-3
Molecular Formula	C32H42O12
Molecular Weight	618.67 g/mol
Synonyms	Wilforlide A monoacetate; (5S,8R,9R,10S,13S,14S,17S)-17-[(2S,3S,5S)-3,5-Dihydroxy-3-methyl-6-oxo-1,6-secoabieta-1(10),7(8),11-trien-12-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,5,15-triyl triacetate; 1,6-Secoabieta-1(10),7(8),11-trien-12-oic acid, 3,5-dihydroxy-3-methyl-6-oxo-, 15-(acetyloxy)-4,4,8,10,14-pentamethyl-17-[(triacetyloxy)methyl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl ester, (5S,8R,9R,10S,13S,14S,17S)-
EINECS	Contact for details

Quality Control

Our Wilforlide A Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with research-grade standards. Specifications can be tailored to meet the requirements of pharmacopeial methods or specific client protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed tightly after each use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with reference structure
Purity (HPLC)	≥95.0% (Area %)
Water Content (KF)	≤5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.