Description

3-Amino-6-Phenylpyrazine-2-Carboxylic Acid is a high-purity, heterocyclic carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both amino and carboxylic acid functional groups on a pyrazine core, makes it an exceptionally versatile intermediate for constructing complex pharmacophores. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive pyrazine scaffold.
• Ligand Synthesis: Serves as a starting material for creating chelating ligands in coordination chemistry and catalysis.
• Material Science: Employed in the research and development of organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology: Utilized as a probe or linker molecule in bioconjugation and the study of biological pathways.
• Custom Synthesis: A fundamental building block for contract research organizations (CROs) and CDMOs performing bespoke synthetic routes.

Basic Information

Product Name	3-Amino-6-Phenylpyrazine-2-Carboxylic Acid
CAS No.	84066-21-7
Molecular Formula	C11H9N3O2
Molecular Weight	215.21 g/mol
Synonyms	3-Amino-6-phenylpyrazine-2-carboxylic acid; 6-Phenyl-3-aminopyrazine-2-carboxylic acid; 2-Pyrazinecarboxylic acid, 3-amino-6-phenyl-; 84066-21-7; 3-Amino-6-phenyl-2-pyrazinecarboxylic acid; 3-Amino-6-phenylpyrazinecarboxylic acid; AKOS005258212; A-6-Phenyl-3-aminopyrazine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Amino-6-Phenylpyrazine-2-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality commitment supports applications requiring high-purity intermediates for research and development under cGMP-like controls where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.