Description

8-Bromo-6-Chloro-3-Methylimidazo[1,2-A]Pyrazine is a high-purity, multi-halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical candidates, particularly in medicinal chemistry programs targeting kinase inhibition and other therapeutic pathways. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical scaffold in the synthesis of potential drug candidates, especially for oncology and CNS diseases.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization studies to explore structure-activity relationships (SAR).
• Agrochemical Synthesis: Acts as a building block for developing new active ingredients with herbicidal or insecticidal properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Material Science Precursor: Potential starting material for creating novel organic electronic materials or ligands for catalysis.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for custom synthesis and scale-up projects under cGMP or non-GMP conditions.

Basic Information

Product Name	8-Bromo-6-Chloro-3-Methylimidazo[1,2-A]Pyrazine
CAS No.	84066-11-5
Molecular Formula	C7H5BrClN3
Molecular Weight	246.49 g/mol
Synonyms	8-Bromo-6-chloro-3-methylimidazo[1,2-a]pyrazine; Imidazo[1,2-a]pyrazine, 8-bromo-6-chloro-3-methyl-; 3-Methyl-8-bromo-6-chloroimidazo[1,2-a]pyrazine; 84066-11-5; 8-Bromo-6-chloro-3-methyl-imidazo[1,2-a]pyrazine; 6-Chloro-8-bromo-3-methylimidazo[1,2-a]pyrazine
EINECS	Contact for details

Quality Control

Our 8-Bromo-6-Chloro-3-Methylimidazo[1,2-A]Pyrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.