Description

Benzyl 3-Methyl-4-Phenylpiperidine-4-Carboxylate Hydrochloride is a high-purity, pharmaceutically relevant piperidine derivative, primarily utilized as a critical synthetic intermediate in advanced organic synthesis. Its value lies in providing a versatile, functionalized scaffold for constructing complex molecules, particularly in medicinal chemistry research and development. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, where it serves as a key building block for the synthesis of potential drug candidates and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Fine Chemical Synthesis: Serves as a versatile precursor for creating complex, functionalized piperidine derivatives used in agrochemicals and specialty materials.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and the exploration of new synthetic pathways.
• Process Chemistry Development: Used in scaling up synthetic routes from laboratory to pilot plant and commercial production scales.

Basic Information

Product Name	Benzyl 3-Methyl-4-Phenylpiperidine-4-Carboxylate Hydrochloride
CAS No.	83898-33-3
Molecular Formula	C20H23NO2 • HCl
Molecular Weight	353.87 g/mol (Hydrochloride salt)
Synonyms	Benzyl 3-Methyl-4-phenyl-4-piperidinecarboxylate hydrochloride; 4-Piperidinecarboxylic acid, 3-methyl-4-phenyl-, benzyl ester, hydrochloride; 3-Methyl-4-phenylpiperidine-4-carboxylic acid benzyl ester hydrochloride; Benzyl 3-methyl-4-phenylisonipecotate hydrochloride
EINECS	Contact for details

Quality Control

Our Benzyl 3-Methyl-4-Phenylpiperidine-4-Carboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.