Description

1-(4-Methoxyphenyl)-4-(p-Tolylsulphonyl)Piperazine is a high-purity, synthetic organic compound featuring a piperazine core functionalized with methoxyphenyl and tosyl groups, serving as a critical advanced intermediate in modern chemical synthesis. Its value lies in providing a versatile and structurally defined building block for the development of novel active pharmaceutical ingredients (APIs) and specialty fine chemicals. This product is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors who require reliable, high-quality intermediates for complex multi-step syntheses.

Application

• As a key pharmaceutical intermediate in the synthesis of potential drug candidates, particularly those targeting neurological or psychiatric disorders.
• Utilized in medicinal chemistry research for structure-activity relationship (SAR) studies and library synthesis due to its modifiable piperazine scaffold.
• Serves as a precursor for the development of specialty fine chemicals and functional materials requiring specific sulfonamide or aryl ether motifs.
• Potential use as a building block in agrochemical research for creating novel active ingredients with enhanced properties.
• Employed in academic and industrial R&D for methodological development in organic synthesis and catalysis.

Basic Information

Product Name	1-(4-Methoxyphenyl)-4-(p-Tolylsulphonyl)Piperazine
CAS No.	83863-43-8
Molecular Formula	C18H22N2O3S
Molecular Weight	346.45 g/mol
Synonyms	1-(4-Methoxyphenyl)-4-(4-methylphenylsulfonyl)piperazine; 4-Methoxy-N-(4-methylphenylsulfonyl)-N'-phenylpiperazine; 4-(4-Methoxyphenyl)-1-tosylpiperazine; 1-Tosyl-4-(4-methoxyphenyl)piperazine; p-Toluenesulfonyl-4-(4-methoxyphenyl)piperazine; 83863-43-8; Tosyl-4-(p-methoxyphenyl)piperazine
EINECS	Contact for details

Quality Control

Our 1-(4-Methoxyphenyl)-4-(p-Tolylsulphonyl)Piperazine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and reliable supply for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.