Description

Leukotriene A3 Methyl Ester is a specialized methyl ester derivative of the leukotriene A3 eicosanoid. This compound serves as a crucial advanced synthetic intermediate and a reference standard in biochemical research. It is primarily utilized by pharmaceutical R&D teams and academic researchers focused on inflammation pathways, lipid mediator synthesis, and the development of novel therapeutics targeting leukotriene receptors.

Application

• Biochemical Research: Used as a key intermediate in the study of leukotriene biosynthesis and metabolism pathways.
• Pharmaceutical Development: Serves as a critical precursor or reference standard in the synthesis of potential anti-inflammatory drug candidates.
• Analytical Standard: Employed as a high-purity standard for method development and validation in analytical techniques like HPLC and LC-MS.
• Cell Signaling Studies: Applied in in-vitro research to investigate the role of leukotriene derivatives in cellular signaling and immune responses.
• Enzymology: Used as a substrate to study the activity and inhibition of enzymes like leukotriene A4 hydrolase or other relevant synthases.
• Metabolite Synthesis: A starting material for the chemical synthesis of downstream leukotriene metabolites for biological evaluation.

Basic Information

Product Name	Leukotriene A3 Methyl Ester
CAS No.	83851-38-1
Molecular Formula	C21H32O3
Molecular Weight	332.48 g/mol
Synonyms	(5S,6S)-5,6-Epoxy-7,9,11,14-eicosatetraenoic Acid Methyl Ester; Methyl (5S,6S)-Oxido-7E,9E,11Z,14Z-eicosatetraenoate; LTA3 Methyl Ester; 5(6)-Epoxy-7,9,11,14-eicosatetraenoic Acid Methyl Ester; Leukotriene A3 Methyl Ester
EINECS	Contact for details

Quality Control

Our Leukotriene A3 Methyl Ester is produced under controlled conditions to ensure high chemical purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including HPLC for purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your research and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Solubility	Soluble in ethanol, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.