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n-[(1-Ethyl-2-Pyrrolidinyl)Methyl]-2-Methoxy-5-(Methylsulphonyl)Benzamide Monohydrochloride CAS NO 83846-73-5
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CAS No.:83846-73-5
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
n-[(1-Ethyl-2-Pyrrolidinyl)Methyl]-2-Methoxy-5-(Methylsulphonyl)Benzamide Monohydrochloride is a high-purity, pharmacologically active compound of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard in the synthesis and analytical validation of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing central nervous system (CNS) and other specialized medications.
Application
- Pharmaceutical Intermediate: A key building block in the synthesis of complex active pharmaceutical ingredients (APIs) for neurological and psychiatric disorders.
- Reference Standard: Used in analytical method development and validation (HPLC, LC-MS) for quality control and regulatory submissions.
- Biochemical Research: Employed in preclinical studies to investigate receptor binding affinity, pharmacokinetics, and metabolic pathways.
- Process Chemistry: Serves as a starting material or intermediate in scale-up and optimization of API manufacturing processes.
- Academic Research: Utilized in university and institutional labs for medicinal chemistry projects and pharmacological studies.
- Impurity Standard: Critical for identifying, quantifying, and controlling process-related impurities and degradation products in final drug substances.
Basic Information
| Product Name | n-[(1-Ethyl-2-Pyrrolidinyl)Methyl]-2-Methoxy-5-(Methylsulphonyl)Benzamide Monohydrochloride |
| CAS No. | 83846-73-5 |
| Molecular Formula | C17H27N2O4S • HCl |
| Molecular Weight | 398.93 g/mol |
| Synonyms | 5-(Methylsulfonyl)-2-methoxy-N-[(1-ethyl-2-pyrrolidinyl)methyl]benzamide Hydrochloride; Remoxipride Related Compound; (S)-(-)-Remoxipride Hydrochloride; L-(-)-Remoxipride Hydrochloride; FLA 731; NCQ 344; Benzamide, 5-(methylsulfonyl)-2-methoxy-N-[(1-ethyl-2-pyrrolidinyl)methyl]-, monohydrochloride; (S)-5-(Methylsulfonyl)-2-methoxy-N-[(1-ethyl-2-pyrrolidinyl)methyl]benzamide Hydrochloride |
| EINECS | Contact for details |
Quality Control
Our n-[(1-Ethyl-2-Pyrrolidinyl)Methyl]-2-Methoxy-5-(Methylsulphonyl)Benzamide Monohydrochloride is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral purity assessment, and identity confirmation to ensure it meets exacting standards for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting regulatory compliance and research integrity.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a low-humidity environment to maintain stability and purity.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference standard |
| Assay (HPLC) | ≥98.0% |
| Chiral Purity (HPLC) | ≥99.0% |
| Water Content (KF) | ≤1.0% |
| Residue on Ignition | ≤0.1% |
| Heavy Metals | ≤20 ppm |
| Related Substances (HPLC) | Individual impurity ≤0.5%; Total impurities ≤1.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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