Description

Falecalcitriol CAS NO 83805-11-2 is a synthetic, biologically active vitamin D3 analog. This compound is of significant interest for its potent regulatory effects on calcium and phosphate metabolism, offering a high degree of biological activity. It is primarily utilized by pharmaceutical research and development teams engaged in creating advanced therapeutic agents for metabolic bone disorders and related endocrine conditions.

Application

• Pharmaceutical Active Ingredient (API): Serves as a key intermediate or active component in the formulation of prescription medications for treating osteoporosis, renal osteodystrophy, and hypoparathyroidism.
• Biochemical Research: Employed in laboratory studies to investigate vitamin D receptor (VDR) signaling pathways, gene regulation, and cellular differentiation processes.
• Metabolic Disorder Studies: Used as a reference standard or experimental compound in preclinical research targeting calcium homeostasis and bone mineralization.
• Advanced Drug Development: Integral to the synthesis and development of next-generation vitamin D analogs with optimized therapeutic profiles and reduced side effects.

Basic Information

Product Name	Falecalcitriol
CAS No.	83805-11-2
Molecular Formula	C₂₉H₄₄O₃
Molecular Weight	440.66 g/mol
Synonyms	1α,25-Dihydroxy-26,27-hexafluoro-19-nor-vitamin D3; 1α,25-Dihydroxy-26,26,27,27,27-pentafluoro-19-norvitamin D3; 1α,25-Dihydroxy-26,27-hexafluoro-19-nor-cholecalciferol; Falecalcitriolum; Hexafluoro-1,25-dihydroxy-19-norvitamin D3; 26,27-Hexafluoro-1α,25-dihydroxy-19-norvitamin D3; 19-Nor-26,27-hexafluoro-1α,25-dihydroxyvitamin D3
EINECS	Contact for details

Quality Control

Our Falecalcitriol is manufactured under strict quality management systems, targeting high-purity standards suitable for pharmaceutical research. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request to ensure full transparency and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Due to its strictly light-sensitive and easily oxidized nature, long-term storage is recommended under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.