Description

Forskolin, 7-Deacetyl-7-o-Hemisuccinyl- CAS NO 83797-56-2 is a chemically modified derivative of forskolin, a bioactive diterpenoid originally isolated from the plant Coleus forskohlii. This semisynthetic derivative is engineered for enhanced solubility and stability, making it a crucial intermediate and reference standard in advanced pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the life sciences sector for investigating and developing novel therapeutic agents targeting cellular signaling pathways.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of more complex, target-specific forskolin analogs for drug discovery programs.
• Biochemical Research: Used as a potent activator of adenylate cyclase to study cyclic AMP (cAMP)-mediated signaling pathways in cell biology and physiology.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for the identification and quantification of forskolin derivatives.
• Metabolic Studies: A tool compound in research focused on lipid metabolism, cardiovascular function, and endocrine regulation.
• Cosmeceutical R&D: Investigated for potential applications in topical formulations targeting skin conditions, leveraging its cell-signaling properties.

Basic Information

Item	Details
Product Name	Forskolin, 7-Deacetyl-7-o-Hemisuccinyl- CAS NO 83797-56-2
CAS No.	83797-56-2
Molecular Formula	C28H38O10
Molecular Weight	534.60 g/mol
Synonyms	7-Deacetyl-7-o-hemisuccinylforskolin; 7-Deacetylforskolin 7-hemisuccinate; 1α,6β,9α-Trihydroxy-8,13-epoxy-labd-14-en-11-one 6-acetate 7-hemisuccinate; 7-O-Hemisuccinyl-7-deacetylforskolin; Colforsin 7-hemisuccinate; NKH477 precursor; NKH 477 intermediate; 7-Deacetylforskolin hemisuccinate ester
EINECS	Contact for details

Quality Control

Our Forskolin, 7-Deacetyl-7-o-Hemisuccinyl- is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.