Description

2,2-Dichloro-3-Oxobutyryl Chloride is a highly reactive acid chloride derivative, serving as a crucial building block in advanced organic synthesis. Its value lies in its bifunctional reactivity, offering both an acyl chloride and a reactive α-chlorinated ketone moiety for sequential transformations. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to construct complex heterocyclic scaffolds and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various heterocyclic compounds, including pyrazoles and isoxazoles, which are core structures in many drug molecules.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, leveraging its reactivity to introduce chlorinated carbonyl functionalities.
• Chemical Research & Development: A versatile reagent for exploring new reaction pathways and creating novel chemical entities in academic and industrial R&D labs.
• Dye and Pigment Manufacturing: Intermediate in the synthesis of specialized dyes and organic pigments that require chlorinated ketone backbones.
• Polymer Chemistry: Can act as a monomer or cross-linking agent for specialty polymers with specific thermal or chemical resistance properties.

Basic Information

Product Name	2,2-Dichloro-3-Oxobutyryl Chloride
CAS No.	83742-29-4
Molecular Formula	C4H3Cl3O2
Molecular Weight	189.42 g/mol
Synonyms	2,2-Dichloro-3-oxobutanoyl Chloride; 3,3-Dichloro-2-oxobutyryl Chloride; 2,2-Dichloroacetoacetyl Chloride; α,α-Dichloroacetoacetyl Chloride; Butanoyl chloride, 2,2-dichloro-3-oxo-; NSC 163063; 1,1-Dichloro-2-oxopropanecarbonyl Chloride
EINECS	Contact for details

Quality Control

Our 2,2-Dichloro-3-Oxobutyryl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of GMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong bases, oxidizers, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.