Description

[1,4'-Bipiperidine]-4'-Carboxamide Dihydrochloride is a high-purity, pharmaceutically relevant organic salt used as a critical intermediate in advanced chemical synthesis. Its value lies in providing a functionalized, nitrogen-rich bicyclic scaffold essential for constructing complex molecules with targeted biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Chemical Synthesis: Serves as a versatile precursor for creating more complex heterocyclic compounds and functionalized piperidine derivatives.
• Ligand and Receptor Studies: Employed in the development of probes and ligands for neurological and pharmacological research.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing specialized compounds for clients.
• Reference Standard: Used as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	[1,4'-Bipiperidine]-4'-Carboxamide Dihydrochloride
CAS No.	83732-56-3
Molecular Formula	C11H22N4O · 2HCl
Molecular Weight	307.24 g/mol (as free base: 226.32)
Synonyms	4-Carbamoyl-1,4'-bipiperidine Dihydrochloride; 1,4'-Bipiperidine-4'-carboxamide Dihydrochloride; 4'-Carbamoyl-1,4'-bipiperidine Dihydrochloride; 4-Piperidinecarboxamide, 1-(4-piperidinyl)-, Dihydrochloride; NSC 339539 Dihydrochloride; Bipiperidyl-4-carboxamide Dihydrochloride
EINECS	Contact for details

Quality Control

Our [1,4'-Bipiperidine]-4'-Carboxamide Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), residual solvents, and other critical parameters is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.