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1,2-Pentadecanoylphosphatidylcholine CAS NO 83588-03-8
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CAS No.:83588-03-8
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
1,2-Pentadecanoylphosphatidylcholine is a synthetic, single-chain phospholipid where both sn-1 and sn-2 positions are esterified with pentadecanoic acid. This well-defined molecular structure makes it a valuable standard and a critical building block for advanced lipid research and formulation development. It is essential for scientists and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require high-purity, chemically-defined lipids for creating model membranes, drug delivery systems, and specialized reagents.
Application
- Lipidomics Research & Analytical Standards: Serves as a critical reference standard for mass spectrometry (MS) and chromatography to identify and quantify complex lipid species in biological samples.
- Model Membrane Systems: Used in the formulation of liposomes and supported lipid bilayers (SLBs) to study membrane biophysics, protein-lipid interactions, and cellular processes.
- Drug Delivery Vehicle Development: Acts as a key excipient in the design and optimization of lipid nanoparticles (LNPs) and liposomal carriers for targeted therapeutic delivery.
- Biochemical Reagent: Employed as a substrate or inhibitor in enzymatic assays to study phospholipase activity and other lipid-modifying enzymes.
- Cosmetic & Dermal Formulations: Incorporated into high-end skincare products for its biomimetic properties, helping to restore and protect the skin's natural lipid barrier.
- Surface Chemistry & Coatings: Utilized to create functionalized surfaces with specific hydrophilic/hydrophobic properties for biosensor and diagnostic device applications.
Basic Information
| Product Name | 1,2-Pentadecanoylphosphatidylcholine |
| CAS No. | 83588-03-8 |
| Molecular Formula | C38H76NO8P |
| Molecular Weight | 706.0 g/mol (approx.) |
| Synonyms | 1,2-Dipentadecanoyl-sn-glycero-3-phosphocholine; PC(15:0/15:0); DPPC (DiPentadecanoyl PhosphatidylCholine); 1,2-Di(pentadecanoyl)-PC; Phosphatidylcholine (15:0/15:0); 3-sn-Phosphatidylcholine, 1,2-di(pentadecanoyl)-; L-α-Phosphatidylcholine, dipalmitoleoyl- (incorrect but common misnomer); Glycerophosphocholine with two C15:0 acyl chains |
| EINECS | Contact for details |
Quality Control
Our 1,2-Pentadecanoylphosphatidylcholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization using techniques including NMR, HPLC, and MS to confirm identity, purity, and lipid composition. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP-grade requirements. Specifications can be tailored to meet specific project needs.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder or waxy solid |
| Identification (NMR) | Conforms to structure |
| Identification (MS) | Conforms to structure |
| Purity (HPLC) | ≥ 95% (Area %) |
| Assay (Phosphorus) | ≥ 98% (of theoretical) |
| Solubility | Soluble in chloroform, methanol; insoluble in water |
| Loss on Drying | ≤ 2.0 % |
| Heavy Metals | ≤ 10 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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