Description

1-0-Octadecyl-2-Butyryl-Sn-Glycero-3-Phosphocholine is a synthetic, structured phospholipid derivative, specifically a lysophosphatidylcholine (LPC) analog with defined acyl chain substitution. This compound is of significant value for its role as a key intermediate and functional lipid in advanced biomedical and materials research. It is primarily needed by pharmaceutical R&D teams, formulation scientists, and manufacturers in the life sciences sector for developing novel drug delivery systems, such as liposomes and lipid nanoparticles (LNPs), and for studying membrane biophysics.

Application

• Lipid Nanoparticle (LNP) Formulation: A critical component for constructing stable, efficient delivery vehicles for mRNA, siRNA, and other nucleic acid therapeutics.
• Liposomal Drug Delivery: Used as a functional excipient to modify the surface properties, stability, and targeting capabilities of liposomes for encapsulated drugs.
• Biomembrane Research: Serves as a well-defined synthetic lipid for studying lipid-protein interactions, membrane fluidity, and model membrane systems.
• Cell Culture & Transfection Reagents: Incorporated into formulations to enhance cellular uptake and transfection efficiency in vitro.
• Diagnostic Reagent Development: Utilized in the preparation of lipid-based reagents for diagnostic assays and imaging applications.
• Cosmetic & Dermal Formulations: Acts as a high-performance emollient and penetration enhancer in advanced skincare products.

Basic Information

Product Name	1-0-Octadecyl-2-Butyryl-Sn-Glycero-3-Phosphocholine
CAS No.	83526-67-4
Molecular Formula	C30H61NO7P
Molecular Weight	578.78 g/mol
Synonyms	1-O-Octadecyl-2-butyroyl-sn-glycero-3-phosphocholine; 18:0-4:0 Lyso PC; 1-Stearyl-2-butyryl-sn-glycero-3-phosphocholine; LysoPC(18:0/4:0); O-Octadecyl-O'-(2-butyryl)-sn-glycerophosphocholine; Butyryl LysoPC; Structured Lysophosphatidylcholine
EINECS	Contact for details

Quality Control

Our 1-0-Octadecyl-2-Butyryl-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.