Description

1,2-Cyclopropanedicarbonyl Dichloride, 1-Methyl-, trans- (9Ci) is a high-purity, reactive chemical intermediate featuring a strained cyclopropane ring system. This compound matters for its role as a key building block in the synthesis of complex, biologically active molecules and advanced materials. Pharmaceutical, agrochemical, and specialty chemical R&D laboratories need it for constructing novel molecular architectures, particularly in the development of new active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and insecticides, leveraging its reactive dichloride groups for efficient coupling.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for creating specialty polymers with unique thermal or mechanical properties.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for cyclopropanation reactions and the construction of complex, stereodefined carbocyclic frameworks.
• Ligand & Catalyst Development: Acts as a starting material for synthesizing novel chiral ligands and organometallic catalysts used in asymmetric synthesis.
• Peptide Mimetic Chemistry: Utilized to introduce rigid, conformationally constrained cyclopropane units into peptide backbones to enhance stability and bioactivity.

Basic Information

Product Name	1,2-Cyclopropanedicarbonyl Dichloride, 1-Methyl-, trans- (9Ci)
CAS No.	83458-10-0
Molecular Formula	C7H8Cl2O2
Molecular Weight	195.04 g/mol
Synonyms	trans-1-Methylcyclopropane-1,2-dicarbonyl dichloride; (1R,2S)-1-Methylcyclopropane-1,2-dicarbonyl dichloride; 1-Methyl-trans-1,2-cyclopropanedicarboxylic acid dichloride; 1-Methyl-trans-cyclopropane-1,2-dicarbonyl chloride; trans-1-Methyl-1,2-cyclopropanedicarboxylic acid dichloride; 1-Methyl-trans-1,2-cyclopropanedicarbonyl dichloride
EINECS	Contact for details

Quality Control

Our production of 1,2-Cyclopropanedicarbonyl Dichloride, 1-Methyl-, trans- (9Ci) adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.