Description

1H-Indole, 4-(1-Methyl-3-Piperidinyl)-, (E)-2-Butenedioate (2:1) is a high-purity, complex organic salt of significant interest in advanced pharmaceutical research and development. This compound matters as a key synthetic intermediate or potential active pharmaceutical ingredient (API) for targeting specific neurological and psychiatric pathways. Pharmaceutical manufacturers and advanced research institutions require this material for the development of novel therapeutic agents, particularly in central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of novel drug candidates.
• Neurological Research: Used in preclinical studies for investigating compounds that interact with serotonin or other neurotransmitter systems, given its indole-piperidine structural motif.
• API Development: Potential use as a salt form of an active pharmaceutical ingredient to improve stability, solubility, or bioavailability.
• Chemical Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Medicinal Chemistry: A valuable scaffold for structure-activity relationship (SAR) studies in the design of new bioactive molecules.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	1H-Indole, 4-(1-Methyl-3-Piperidinyl)-, (E)-2-Butenedioate (2:1)
CAS No.	83363-32-0
Molecular Formula	C18H22N2O4 • C4H4O4
Molecular Weight	Contact for details
Synonyms	4-(1-Methyl-3-piperidinyl)-1H-indole fumarate (2:1); Fumaric acid, compd. with 4-(1-methyl-3-piperidinyl)-1H-indole (2:1); 4-(1-Methylpiperidin-3-yl)-1H-indole fumarate salt; 4-(N-Methyl-3-piperidyl)indole fumarate; 83363-32-0; 4-(1-Methyl-3-piperidinyl)indole fumarate
EINECS	Contact for details

Quality Control

Our 1H-Indole, 4-(1-Methyl-3-Piperidinyl)-, (E)-2-Butenedioate (2:1) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets exacting standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). The product is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere when appropriate to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.